Portella PD, et al. - A sum of 728 kids were estimated to assess the consequence of molar incisor hypomineralization (MIH) on oral health-related quality of life (OHRQoL) in kids with early mixed dentition. Using a structured questionnaire, they obtained demographic and socioeconomic data (DSE) from the children's parents/caregivers. They performed the analysis of OHRQoL determinants through a 3-level hierarchical approach: mesial (DSE), intermediate (clinical conditions), and distal (child's oral self-perception), using Poisson regression with robust variance (α=0.05). They observed 12.1%, prevalence of MIH. After adjusting for other clinical variables and DSE, they reported a correlation between MIH and OHRQoL in the "oral symptoms" domain of the CPQ8-10. They concluded an association of molar incisor hypomineralization with a greater impact on OHRQoL in children's oral symptoms.