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Impact of handgrip strength on cardiovascular, cancer and all-cause mortality in the Korean longitudinal study of ageing

BMJ Open May 13, 2019

Kim GR, et al. - To evaluate the risk of cardiovascular, cancer, and all-cause mortality linked with muscular weakness, investigators examined older individuals for reduced handgrip strength. A sum of 5,859 individuals aged > 50 years were included, and they were followed-up until death or date of censoring (December 31, 2014). Of these participants, 515 died, providing a crude mortality rate of 11.0 deaths per 1,000 person-year. Individuals who demonstrated the lowest handgrip strength reflected a higher risk of cardiovascular and all-cause mortality. Patients with cancer had no difference in their death rates. In this Korean population, low handgrip strength was found to be an independent marker of mortality. The investigators stressed the importance of interventions targeted at improving muscle strength for more favorable survival outcomes among the elderly.

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