Hayashida M, Miki A, Imai H, et al. - In this retrospective review, researchers examined the effectiveness of early surgical intervention for dense vitreous hemorrhage (DVH) with unknown etiology. For this investigation, they analyzed 88 cases (88 eyes) of DVH with unknown origin. The criteria for inclusion were as follows: measured visual acuity of 20/200 or worse and fundus invisibility requiring B-scan ultrasonography. Eyes with a history of diabetic retinopathy, recent trauma, or likely retinal detachment (RD) as revealed by B-scan ultrasonography have been excluded. Central or branch retinal vein occlusion and retinal tear or RD were the most frequently occurring causes of DVH. Findings suggested that surgical intervention may prevent a lower visual outcome within 2 weeks of the onset of symptoms.