Radosa JC, et al. - Researchers conducted this prospective randomized controlled study of 178 female patients undergoing laparoscopic hysterectomy for benign uterine pathologies in order to assess how two different intraoperative CO₂ pressures (8 and 15 mmHg) influence the postoperative abdominal and shoulder pain, laparoscopy-mediated vegetative alterations, pain medication requirement, arterial CO₂ pressure (pCO₂), surgical parameters and safety, in these patients. Outcomes revealed significantly lower postoperative abdominal and shoulder pain scores, less vegetative alterations, lower pain medication requirements, a shorter postoperative hospitalisation and lower intra - and postoperative arterial pCO₂ values among patients in the low-pressure group (LP; 8 mmHg, experimental; n = 91) vs the standard pressure group (SP; 15 mmHg; n = 87). The groups did not differ in intra - and postoperative complications.