Yan W, et al. - An inquiry was carried out of the natural innate and adaptive immunity through gene expression and cytology levels in peripheral blood mononuclear cells, in patients with acute myocardial infarction (AMI), stable angina pectoris (SAP) and controls. A decrease was noted in both of the gene expressions related to complement, natural killer cells, CD3+, CD8+ T cells, B cells and the quantity of these immune cells in AMI patients. On the other hand, cell number reduced in SAP patients. Immune function in both AMI and SAP patients decreased particularly among AMI patients with declined gene and protein levels. The potential target for medical interventions and prevention in AMI was the improvement of the immune system.