Lin DW, et al. - Experts created and validated a cell-cycle risk (CCR) score threshold to improve the identification of men with low-risk biopsy-confirmed prostate cancer who were appropriate for active surveillance (AS). Patients were appropriately dichotomized into low- and high-risk groups for 10-year prostate cancer mortality (PCM) with the CCR score threshold. This threshold could enable more appropriate selection of patients for AS. Authors did not note any prostate cancer-specific deaths in men with CCR scores below the threshold in either analysis. Compared to clinicopathologic features alone (42.6%), the proportion of men in the clinical testing cohort identified as candidates for AS was substantially higher using the threshold (68.8%), while mean 10-year predicted PCM risks remained essentially identical.