Zaigham M, et al. - Since it is not clear whether perinatal acidosis in extremely preterm infants can predict poor outcomes, researchers examined connections between intrapartum hypoxia and mortality and neurodevelopmental outcomes. In addition, they estimated correlations between low blood gas values (< 10th percentile) and mortality and neurodevelopmental outcome. Nationwide data on 705 infants from the Extremely Preterm Infants in Sweden Study were used, delivered during 2004-2007 at 22-26 weeks of gestation. Investigators found that cord blood determination was more common in surviving infants, with pH determined in 322/705 (46%) and base excess in 311/705 (44%). They observed that extremely preterm infants had higher pH values compared with term infants, with no change from 22 to 26 weeks of gestation. According to multiple logistic regression, no connection was found between low blood gas values and risk of death or neurodevelopmental impairment at 6.5 years. In extremely preterm born children at 6.5 years of age, hypoxia with acidosis at birth was not linked to an increased risk of death or impaired neurodevelopmental.