Anlló H, Herer B, Delignières A, et al. - Whether in patients suffering from severe chronic obstructive pulmonary disease (COPD), a 15-minute hypnosis intervention could bring about immediate improvement of anxiety, was determined in this study. A total of 21 patients with COPD (mean FEV1 < 32.3%) took part in this study, of whom 19 (90.5%) completed the study. The patients were randomized to two individual sessions in crossover (sham and hypnosis, 24-h washout period, arms: hypnosis-sham [n = 11]/sham-hypnosis [n = 10]). The primary endpoint was pre- and post-intervention anxiety (STAI-6 score). The participants who engaged in a 15-minute hypnosis session experienced improvement of anxiety and lower respiratory rate (as opposed to sham). There was a correlation between improvements in anxiety and an alleviation in respiratory strain. Based on these data, experts concluded that hypnosis is capable of resulting in improvement of anxiety levels and breathing mechanics among patients with severe COPD.