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Hypertension development by midlife and the roles of premorbid cognitive function, sex, and their interaction

Hypertension Feb 24, 2019

Altschul DM, et al. - Researchers investigated whether higher early-life cognitive function was related to lower hypertension risk in women vs men. They used accelerated failure time modeling with the National Longitudinal Study of Youth 1979. Between 14 and 21 years, evaluation of cognitive function was carried out among participants. Overall, all assessments were completed by 2,572 men and 2,679 women. Among these, hypertension diagnoses by the year 2015 were reported in 977 men and 940 women. As covariates, they investigated socioeconomic status in youth and adulthood, as well as education, occupational status, and family income (as components of adult socioeconomic status). Findings revealed a lower likelihood of developing hypertension later in life among those who had better cognitive function in youth; this was especially seen in women. These links were attributed to income disparities.

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