Furashova O, et al. - Researchers conducted this retrospective and observational case series to examine the reflectivity changes of inner retinal layers in acute retinal vein occlusion (RVO) on spectral-domain optical coherence tomography and to compare these values with other known parameters of acute ischemic damage. Two hundred thirty eyes from 115 patients with acute RVO (central or branch) were categorized as ischemic or non-ischemic depending on fluorescein angiography (FA) images at baseline. In the ischemic vs non-ischemic type, acute RVO results in increased reflectivity of inner retinal layers with significantly higher values. Increased reflectivity of the inner retinal layers was significantly associated with BCVA, the retinal thickness of separate retinal layers, and ischemic area on FA. Quantitative non-invasive measurement of reflectivity of the inner retinal layers could be used to determine the extent of acute ischemic retinal damage in RVO.