Giers BC, et al. – The purpose of this study is to investigate the hydrophilic intraocular lens opacification after posterior lamellar keratoplasty. The outcome suggests the instillation of exogenous material such as air or gas into the anterior chamber increases the risk for opacification of hydrophilic intraocular lenses (IOLs) irrespective of the manufacturer or the exact composition of the hydrophilic lens material. It is suggested to avoid the utilization of hydrophilic acrylic IOLs in patients with endothelial dystrophy that will likely require procedures involving the intracameral instillation of air or gas, such as descemet membrane endothelial keratoplasty (DMEK) or DS(A)EK.