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Hydrogen and methane breath test results are negatively associated with IBS and may reflect transit time in post-surgical patients

Neurogastroenterology & Motility Jun 04, 2021

Essa H, Hamdy S, Green D, et al. - Researchers sought to review the clinical features of a large cohort of patients to determine which factors are associated with positive and negative hydrogen and methane breath test results, in order to better understand their role in clinical practice. Over a 3-year period, 525 glucose hydrogen/methane breath tests were analyzed to look for positively and negatively associated predictive factors. Characteristics like height and weight and underlying medical conditions, medications, and surgical history have been collated. Findings revealed that there were 85 and 42 positive hydrogen and methane tests, respectively. According to the findings, patients with irritable bowel syndrome are statistically less likely to have a positive test, making it of limited usefulness in this group. A significantly negative connection with motility-suppressing medicines in this sub-group suggests that post-surgical patients are more likely to get a positive test, presumably due to quick transit rather than bacterial overgrowth.

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