Chhana A, Pool B, Wei Y, et al. - From macroscopically healthy and macroscopically diseased knee joint samples, Human cartilage homogenates were prepared in order to investigate the impacts of human cartilage homogenates on monosodium urate (MSU) crystallization and MSU crystal-induced inflammation. It was discovered that in the presence of raised urate levels, human cartilage homogenates raise MSU crystal formation and encourage the formation of smaller crystals, which have more comprehensive inflammatory potential. Moreover, these processes may add to the inclination of osteoarthritic joints to develop gout.