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How obstructive sleep apnea evolves from childhood to young adulthood – natural history from a 10-year follow-up study

Chest Mar 29, 2019

Chan KC, et al. - In this longitudinal analysis of a prospective community-based cohort, researchers assessed the natural history of childhood obstructive sleep apnea (OSA) as well as studied the factors related to spontaneous remission, persistent and incident OSA from childhood to late adolescence / early adulthood. The included participants were 243 (59% male), with a mean age of 9.8 (±SD1.8) and 20.2 (±SD1.9) years, at baseline and follow-up respectively. Participants were followed-up for a mean duration of 10.4 (±SD1.1) years. They found that during the transition to late adolescence or early adulthood, complete resolution occurred in a proportion of children with OSA, especially female. Differences were seen between childhood and adolescent OSA, persistence into adulthood was more likely to be seen in adolescent OSA. Important and consistent risk factors for incident OSA were obesity and male gender.
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