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Hospitalizations among adults with chronic kidney disease in the United States: A cohort study

PLoS Medicine Feb 15, 2021

Schrauben SJ, Chen HY, Lin E, et al. - Given that hospitalizations of chronic kidney disease (CKD) adults is more frequent than that of those without CKD, however, there is not proper understanding of the magnitude of this excess morbidity as well as the factors related to hospitalizations, and therefore, these topics were addressed herein by analyzing data from 3,939 individuals registered in the Chronic Renal Insufficiency Cohort Study between 2003 and 2008. A higher hospitalization rate was reported in adults suffering from CKD vs the general population that was hospitalized, and increased rates of hospitalization were documented in relation to even moderate decreases in renal function. Reasons for hospitalization were mainly associated with cardiovascular disease, but there were other contributors also, especially genitourinary, digestive, and endocrine, nutritional, and metabolic diseases. High levels of proteinuria displayed the largest link with hospitalizations across a broad range of renal function levels.

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