Perrissin-Fabert M, Stheneur C, Veilleux-Lemieux M, et al. - Researchers performed a cohort retrospective chart review to examine the effect of hormonal contraception (HC) on lung function in adolescent cystic fibrosis (CF) population by evaluating the forced expiratory volume in 1 second (FEV1), the number of exacerbations of pulmonary condition, and antibiotic use. The sample consisted of 127  girls, aged 13 to 18 years, who were followed in the CF clinic of a university hospital center. FEV1 at 18 years of age was significantly higher for girls taking HC for more than 3 years than for girls who had never taken HC at all. However, there was no disparity between these 2 groups in the number of hospital admissions for exacerbation of the pulmonary condition. No difference was found between HC vs non-HC users in the percent of patients taking antibiotics by nebulizer over the 6 years of follow-up. The research indicates HC has no deleterious impact on the FEV1 in adolescents with CF.