Wang AY, et al. - In order to define the role of HMG-CoA reductase inhibitors (statins) in high mortality observed in intensive care unit (ICU) patients with acute kidney injury (AKI), researchers performed this secondary analysis of RENAL Study (Randomized Evaluation of Normal versus Augmented Level Replacement Therapy) outcomes and focused on the link between the use of HMG-CoA reductase inhibitors (statins) and all-cause mortality among participants requiring dialysis in ICU, using multivariate Cox modelling. No link was found between baseline statin use and mortality in the RENAL study cohort. A protective role of statins in ICU patients with severe AKI was not supported in this study.