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Higher triglyceride to high-density lipoprotein cholesterol ratio increases cardiovascular risk: 10-year prospective study in a cohort of Chinese adults

Journal of Diabetes Investigation Dec 15, 2019

Chen Z, Chen G, Qin H, et al. - During a 10-year follow-up period, researchers analyzed the association of triglyceride to HDL cholesterol ratio (TG/HDL-C) with cardiovascular (CV) risks among Chinese adults. The sample for this prospective study consisted of 96,542 patients (mean age: 51.5 ± 12.6 years) who were clustered through the median value (0.8533) of TG/HDL-C ratio. Through Cox proportional hazard models, the risk of CV events were estimated. In all, 5,422 major CV events took place during a median follow up of 9.75 years, including 1,312 cases of myocardial infarction (MI) and 4,228 cases of stroke. The cumulative incidence of MI, stroke, and total CV events was 1.36%, 4.38% and 5.62%, respectively. A higher TG/HDL-C ratio was associated with an increased risk of major CV events among the Chinese population. The authors noted that their findings may help public policymakers formulate a strategy for high-risk individuals in the Chinese population for major CV events.

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