Kubo S, et al. - In this cross-sectional study including a Japanese general community population without chronic kidney disease (CKD), researchers examined the link between serum uric acid (SUA) levels and kidney function assessed by cystatin C. This study included 1086 healthy subjects (aged 40–74 years) who had participated in the baseline survey of the Kobe Orthopedic and Biomedical Epidemiological (KOBE) study and were not receiving treatment of hyperuricemia. Inclusion criteria for this study required participants to have no past histories of cardiovascular disease or cancer, and not undergoing treatment for diabetes, hypertension, or dyslipidemia. In this study populace, findings revealed a graded inverse link between mild elevations in SUA levels and estimated glomerular filtration rate (eGFR) assessed by cystatin C; this link was similar in both sexes.