Ran Y, Wang Y, Zhu M, et al. - Using magnetic resonance vessel wall imaging, researchers intended to determine if there is a connection between the features of atherosclerotic plaques of a middle cerebral artery and recurrent ischemic stroke by multivariate analysis. For this investigation, 105 individuals with ischemic stroke attributed to middle cerebral artery plaque had high-resolution black-blood magnetic resonance vessel wall imaging. Participants in the study were divided into group 1, with the first episode of acute stroke (imaging within 4 weeks of stroke, n = 44); group 2, with recurrent acute stroke (n = 29); and group 3, with chronic stroke (imaging after 3 months of stroke, n = 32). Compared with the other 2 groups (median: group 2, 82.7%, vs group 1, 76.3%, and group 3, 73.4%), plaque burden was significantly greater in the recurrent stroke group. Recurrent stroke patients were older, more likely with female sex and hypertension, and had higher plaque burden comparing to first-onset acute stroke individuals. Plaque burden was the only independent imaging feature related to recurrent stroke after adjustment of clinical factors.