Crawford DA, et al. - Through a retrospective review of 1,611 individuals (2,038 knees) who underwent total knee arthroplasty (TKA) with a 5-year minimum follow-up, researchers reported on implant survivorship and outcomes of high activity patients in comparison with low activity patients following TKA. Significantly more women patients, older with higher BMI, and lower functional scores preoperatively were observed in the low activity (LA) group. Significantly greater improvements in Knee society scores and pain following the operation was noted in the high activity (HA) group. In 4% and 1.7% knees of the LA group and of the HA group, respectively, revisions were done. A greater postoperative activity level continued to be an important factor for improved survivorship with an OR of 2.4, after controlling for age, gender, preoperative pain, KSC, KSF, and BMI. For the HA group and for the LA group, the all-cause 12-year survivorship was 98% and 95.3%, respectively. The aseptic 12-year survivorship was 98.4% and 96.3%, respectively, for the HA group and for the LA group. Therefore, at 5-year minimum follow-up, in comparison with lower activity individuals following TKA, highly active individuals had progressed survivorship. Patient activity level following TKA may not require to be limited with modern implants.