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High prevalence of osteopathy in chronic pancreatitis: A cross-sectional analysis from the PROCEED study

Clinical Gastroenterology and Hepatology Oct 20, 2021

Hart PA, Yadav D, Li L, et al. - Presence of osteopathy was evident in the majority of cases in this largest study of patients with chronic pancreatitis (CP) who underwent dual-energy X-ray absorptiometry (DXA) screening. There exist overlapping risk factors with osteopathy in the general population, however, men and younger women exhibit a high prevalence.

  • This is a prospective analysis of 282 patients with definitive CP enrolled in the PROCEED study who underwent a baseline DXA scan.

  • DXA scan detected osteopathy in most of the cases (56.0%; 17.0% osteoporosis; 39.0% osteopenia).

  • A higher prevalence of traumatic (40.0% vs 26.4%) and spontaneous fractures (3.9% vs 0) was identified in participants with osteopathy.

  • Factors related to higher likelihood of osteopathy were: older age (odds ratio [OR], 1.29 per 5 years), female gender (OR, 3.08), white race (OR, 2.68), and underweight body mass index category (OR, 7.40).

  • No significant links exist between osteopathy and patient and disease-related features of CP.

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