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High prevalence of hepatic fibrosis, measured by elastography, in a population-based study of Mexican Americans

Clinical Gastroenterology and Hepatology Mar 27, 2019

Watt GP, et al. - In a population-based study of Mexican American Hispanics in south Texas, researchers identified the prevalence of significant fibrosis, measured by point shear-wave elastography (pSWE), and determined characteristics of hepatic fibrosis and simple steatosis. For 406 participants in the Cameron County Hispanic Cohort from 2015 to 2017, pSWE, performed by two separate operators, measured liver stiffness. Data indicated that significant fibrosis prevalence was 13.8%. Fibrosis and simple steatosis were related to levels of liver enzymes. Simple steatosis was significantly associated with metabolic health indicators (insulin resistance, triglycerides, and cholesterol). Fibrosis was significantly related to antibodies to HCV in plasma, but not simple steatosis, and was not significantly linked to reduced platelet counts. Investigators found that Mexican American Hispanics had a higher fibrosis prevalence compared to European and Asian populations, primarily due to metabolic disease.
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