Glagn Abdilwohab M, et al. - Researchers performed a community-based cross-sectional study to evaluate the prevalence of clinically active trachoma and its associated risk factors among preschool-aged children in Arba Minch Health and Demographic surveillance site, Southern Ethiopia. This investigation was conducted among 831 preschool children (children aged 2–5 years) from May 01 to June 16, 2019. Data reported that the overall prevalence of clinically active trachoma among preschool-aged children was 17.8% with 95% CI. Among pre-school aged children, the prevalence of clinically active trachoma was high. The SAFE strategy's “Facial cleanliness” and “Environmental improvement” components are vital components in working towards the 2020 trachoma elimination goal. Therefore, stakeholders from various hierarchies need to make ongoing efforts to integrate the trachoma prevention and control programs with other public health programs, with water sanitation and hygiene programs and with the education system.