Oosterwijk MM, Groothof D, Navis G, et al. - No increase in the hazard of kidney function deterioration was brought about by unrestricted dietary protein intake in patients with type 2 diabetes (T2D), thus, replacing carbohydrates with dietary protein is not contraindicated as a component of T2D management, although it could exert a positive impact on body weight while minimizing loss of muscle mass.

• Data of 382 patients of the Diabetes and Lifestyle Cohort Twente (DIALECT) study were used to examine the prospective link between dietary protein consumption and kidney function deterioration in T2D patients.

• An inverse correlation of dietary protein intake with renal function deterioration was found (hazard ratio HR: 0.62).

• An elevated hazard for renal function deterioration (HR 1.44) was observed in relation to an intake <92 g/day, while a decreased hazard was evident for an intake >163 g/day (HR 0.42).

• Concerning dietary protein consumption per kilogram body weight, there was an increased hazard for renal function deterioration in patients with an intake <1.08 g/kg/day (HR 1.63).