Getachew M, Lerdal A, Smastuen MC, et al. - A longitudinal cohort study was performed to evaluate whether high levels of preoperative pain and fatigue are red flags for moderate‐severe pain 12 months after total knee arthroplasty. Researchers included a total of 202 individuals who had undergone primary total knee arthroplasty (TKA) in a longitudinal cohort study. After TKA, the pain was re‐assessed 12 months. They applied logistic regression analysis to calculate the probabilities of moderate‐severe pain at 12 months based on preoperative symptom levels, and results were combined into a risk matrix. It was shown that the combination of high fatigue and pain scores prior to surgery was a key risk factor for moderate‐severe pain 12 months after TKA. As per the results, mapping of these factors could be applied preoperatively to distinguish individuals who are at risk to experience a poor outcome of TKA.