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High iodine dietary intake is associated with type 2 diabetes among women of the E3N-EPIC cohort study

Clinical Nutrition Aug 30, 2018

Mancini FR, et al. - Researchers, for the first time, investigated whether there was an association between iodine intake and the risk of type 2 diabetes. They used Cox proportional hazards regression models adjusted on potential confounders to calculate the hazard ratios and 95% confidence intervals for the correlations between dietary iodine intake and type 2 diabetes risk among 71,264 women of the E3N-EPIC cohort. The study population had an average iodine intake of 155.6 μg/day (±47.1 μg/day). The hazard ratios (95% CI) for type 2 diabetes of women in the 4th (160.7-190.5 μg/day) and 5th (190.6-596.8 μg/day) quintiles groups of iodine intake were 1.27 (1.10-1.47) and 1.28 (1.07-1.53), respectively after adjusting for the main risk factors for diabetes, for hypo/hyperthyroidism, as well as for phosphorus intakes and consumption of dairy products and seafood, compared to women with iodine intake below the 1st quintile (29.3-116.9 μg/day).
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