Kim DS, et al. - The target of this paper was to investigate the hypothesis that genetic polymorphisms are responsible for the low (beta)-cell function and that dietary factors interact with the genes to exacerbate their risk of type 2 diabetes (T2DM). The obtained data deemonstrate that 72 percent of the Korean population had either medium or high genetic risk scores for impaired insulin secretion, which approximately doubled their risk of type 2 diabetes, and the risk was exacerbated by consuming a low carbohydrate Western-style diets.