Mancini ER, et al. – This research incorporated an inquiry of the correlation between phosphorus intake and incidence of type 2 diabetes. The obtained results possibly displayed significant public health implications for dietary recommendations in the prevention of type 2 diabetes. Additional research was necessitated to comprehend the biological mechanisms underlying this positive link.

Methods

• For this trial, 71,270 women from the French E3N-EPIC cohort were examined.
• Among these, 1845 cases of incident type 2 diabetes were validated during follow-up (1993–2011).
• Adjusted Cox proportional hazards regression models estimated the hazard ratios and 95% confidence intervals (95% CI) for the link between phosphorus intake and type 2 diabetes risk, adjusted on potential confounders.

Results

• The data reported the overall mean (±SD) phosphorus intake as being 1477 mg/day (±391 mg/day).
• A correlation was noted between high phosphorus intakeand the risk of type 2 diabetes.
• In multivariate models, compared with women in the 1st quartile of phosphorus intake (<1203 mg/day), those included in the 2nd (1203-1434.0 mg/day), 3rd (1434-1700 mg/day), and 4th (>1700 mg/day) were found to be at a greater risk of type 2 diabetes, with a hazards ratios (95% CI) of 1.18 (1.00-1.38), 1.41 (1.20-1.66) and 1.54 (1.25-1.90), respectively.