Karachaliou M, de Sanjose S, Roumeliotaki T, et al. - Utilizing cross-sectional (n = 686) and prospective (n = 440) data from children partaking in the Rhea birth cohort, researchers sought to explore the correlation of fourteen common viruses with eczema, asthma and rhinoconjunctivitis in childhood. Fluorescent bead-based multiplex serology was used to measure IgG to polyomaviruses (BKPyV, JCPyV, KIPyV, WUPyV, HPyV6, HPyV7, TSPyV, MCPyV, HPyV9, HPyV10) and herpesviruses (EBV, CMV, HSV-1, HSV-2) at age four. Less likely to have eczema at age four were KIPyV and HPyV6 seropositives than their seronegative counterparts. Infections and allergic diseases showed a heterogeneous trend, with common infections linked to a lower risk of eczema and a higher risk of asthma in children. Immune biomarkers did not appear to play a role in mediation.