Niederer RL, Meyer JJ, Liu K, et al. - Researchers conducted this retrospective cohort study to determine the rate of moderate and severe vision loss following herpes zoster ophthalmicus (HZO) and to identify associated factors. All patients with acute HZO seen at a single center from 2006 to 2016 were involved in the study. Eight hundred sixty-nine patients with acute HZO were identified with a median follow up time of 6.3 years (IQR 3.7 – 8.9). Conjunctivitis, followed by keratitis and uveitis, were the most common sites of ocular involvement. Among people with HZO, nearly 1 in 10 people may develop moderate or severe vision loss, primarily due to corneal scarring. Severe permanent vision loss secondary to HZO is associated with older age, immunosuppression, and uveitis.