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Herbal medicinal product use during pregnancy and the postnatal period: A systematic review

Obstetrics and Gynecology Apr 30, 2019

Muñoz Balbontín Y, et al. - Researchers sought to inscribe the incidence and nature of herbal medicinal products' adverse events and herb–drug interactions used by some pregnant and postnatal women via analyzing 3,487 citations retrieved on the topic, from the Allied and Complementary Medicine Database, the Cumulative Index to Nursing and Allied Health Literature, EMBASE, the Cochrane Library, MEDLINE, Scopus, Web of Science, and ClinicalTrials.gov. They included 74 articles for data extraction and synthesis after excluding irrelevant and low-quality articles. This review included a total of 47 herbal medicinal products and 1,067,071 women. The studies reported preterm birth in correlation to the use of almond oil, cesarean delivery in correlation to oral raspberry leaf use; early preterm birth by 3.07-fold in correlation to heavy licorice use. In addition, they observed association of African herbal medicine mwanaphepo with maternal morbidity, and neonatal death or morbidity. These findings emphasize discouraging the use of herbal medicinal products during pregnancy and the postnatal period until robust evidence of their safety is available.
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