Ma B, Sun H, Zhu B, et al. - In this cross-sectional study involving 297 patients with obesity and 43 healthy people with a normal BMI, researchers examined the triangular connection between iron and hepatic steatosis and laparoscopic sleeve gastrectomy (LSG). In obese patients with metabolic disorders, the iron level was elevated. Iron was significantly elevated in patients with obesity or overweight vs individuals with normal BMI. Iron was positively linked with body weight, BMI, waist-to-hip ratio, uric acid, liver enzymes, postprandial blood glucose, fasting insulin, HOMA-IR, triglycerides, free fatty acid, and hepatic steatosis (CAP value), and negatively associated with high-density lipoprotein cholesterol. Iron levels and CAP values were gradually decreased 6 months and 1 year after surgery. The findings showed that, in obesity, iron is correlated with hepatic steatosis. In patients with severe non-alcoholic fatty liver disease (NAFLD), the iron level was significantly higher than with mild or moderate NAFLD. Although improving fat deposition in the liver, LSG can decrease iron levels.