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Hemoglobin levels in early pregnancy and severe maternal morbidity: Population‐based cohort study

BJOG: An International Journal of Obstetrics and Gynaecology Apr 10, 2020

Ray JG, et al. - Researchers conducted a population‐based cohort study investigating the relation between early maternal hemoglobin concentration and severe maternal morbidity (SMM) or maternal mortality. At Ontario, Canada, they assessed 737,393 births with a routine outpatient hemoglobin measured at a calculated gestational age of 2–16 weeks in a public healthcare system. Observations revealed the mean hemoglobin concentration of 126.9 (9.3) g/l. A gradual increase in the risk of SMM or death, as well as red cell transfusion, was observed starting from the lower level of the normal range of hemoglobin of non‐pregnant women. Higher future risk of morbidity, death and blood transfusion was thus suggested for women with low hemoglobin in early pregnancy.

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