Tonmukayakul U, Imms C, Mihalopoulos C, et al. - Researchers examined the link between upper-limb impairment and health-related quality of life (HRQoL) for pediatric patients with cerebral palsy, as well as, they intended to construct a mapping algorithm from the Cerebral Palsy Quality of Life Questionnaire for Children (CPQoL-Child) onto the Child Health Utility 9D (CHU9D) measure. In 76 children, including 40 females and 36 males, aged 6 to 15 years (mean age 9 years 7 months [SD 3y]), they evaluated the links between physical and upper-limb classifications and HRQoL. They developed as well as examined 5 statistical techniques, which predicted the CHU9D scores from the CPQoL-Child total/domain scores, age, and gender. As per the findings, the restricted range of impairment levels of the participants may explain the observed weak negative links between classification levels and HRQoL measures. The influence of upper-limb impairment on HRQoL was better explained by Manual Ability Classification System and Neurological Hand Deformity Classification vs other classifications. The suggested mapping algorithm comprised the generalized linear model with participation, pain, and age. The application of CPQoL-Child for economic assessment will be facilitated by the suggested mapping algorithm, as well as this algorithm can be utilized to perform cost-utility analyses.