Nickel B, et al. - Authors assessed 1,005 subjects (aged 18 to 79 years) from the major postsurgical thyroid cancer treatment center and the population-based Cancer Registry in Queensland, Australia, to evaluate health-related quality of life (HRQOL) following diagnosis and treatment of differentiated thyroid cancer (DTC) and how it is impacted by the type of surgical treatment received. About 88.6% of participants were diagnosed with papillary thyroid cancer; 56.4% of them were identified with tumors less than 2 cm in size and received a total thyroidectomy. They observed subjects diagnosed with DTC had wide-range of HRQOL issues, including physical (66.0%), lifestyle (8.2%) and psychological (18.6%) issues. Candidates with hemithyroidectomy were noted with negligible unfavorable consequences and better HRQOL results vs those who had a total thyroidectomy.