Kelly J, et al. – This qualitative study aims to examine health practitioners’ understanding and practice behaviours regarding clinical prediction rules (CPRs) and investigate their perceptions of adopting a new whiplash CPR. The authors conclude that education on CPR purpose and fit with practice are required to improve the perceived acceptability of CPRs. Strategies that facilitate practitioner motivation, enable administrative flexibility and assist clinicians in communicating the results of the whiplash CPR can promote adoption of the whiplash CPR.