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HbA1c variability in adults with type 1 diabetes on continuous subcutaneous insulin infusion (CSII) therapy compared to multiple daily injection (MDI) treatment

BMJ Open Jan 08, 2020

Scott ES, McGrath RT, Januszewski AS, et al. - In this retrospective audit of clinic records from people with T1DM from two tertiary Australian hospitals, experts intend to discover whether continuous subcutaneous insulin infusion (CSII) therapy was correlated with lower glycated hemoglobin (HbA1c) variability (long-term glycaemic variability; GV) related to multiple daily injection (MDI) treatment in adults (n = 506) with T1DM. Fifty-six adults transitioned from MDI to CSII. It was found that in clinical practice with T1DM adults associated with MDI, CSII therapy was correlated with lower HbA1c GV, irrespective of comparable mean HbA1c levels across the two modalities.
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