Wearing J, et al. - In a cross-sectional study, researchers assessed handgrip strength in the Swiss-German population aged 75 and over, given that an attenuation in handgrip strength below a certain threshold severely increases the risk of mobility limitations and is predictive for adverse outcomes such as dependence in daily activities and mortality. In 244 Swiss people aged 75 years and over (62.7% women), with mean age (SD) of 84.5 (5.6) years in men and 83.1 (5.9) years in women, assessments of maximal isometric handgrip strength of the dominant hand was carried out. In both sexes, advancing age was accompanied with decreased grip strength but men still had greater decline compared to women. Nonetheless men across all age groups had remarkably higher grip strength. Despite having greater grip strength than that reported in other European countries, 50% of the Swiss population sample were still classified as at risk of mobility limitations. In a representative sample of the Swiss population, aged 75–99 years, the age- and sex-stratified reference values for handgrip strength were documented in this study.