Crabtree NJ, et al. - In this pragmatic longitudinal study authors compared growth, body mass, bone mineral density (BMD), vertebral fractures (VF) and ambulatory status in boys with Duchenne muscular dystrophy (DMD) between daily or intermittent oral glucocorticoids (GC) regimens. At the cost of more vertebral fractures, greater adiposity and markedly diminished growth, more boys on daily GCs were seen to remain ambulant. On the contrary, fewer vertebral fractures were seen in boys on intermittent GCs, however, more boys lost independent ambulation.