Adams CB, Johnston WH, Deulofeut H, et al. - Researchers conducted this prospective, multi-center, double-blind, controlled, parallel group study to assess the growth of healthy term infants who received extensively hydrolyzed (EH) or amino acid (AA)-based formulas with reduced protein. Infants were randomly assigned to either a marketed EH casein infant formula with 2.8 g protein/100 kcal (Control) or one of two investigational formulas: EH casein formula at 2.4 g protein/100 kcal (EHF) or AA-based formula at 2.4 g total protein equivalents/100 kcal (AAF). In this study, hypoallergenic infant formulas with 2.4 g protein/100 kcal were found to be safe, well-tolerated, and associated with appropriate growth in healthy term infants aged 14 to 120 days.