Woods GN, Ewing SK, Sigurdsson S, et al. - In order to determine if bone loss and fractures could be predicted by bone marrow adiposity, researchers analyzed older adults in order to examine the links between ¹H-MRS–based measures of vertebral bone marrow adipose tissue (BMAT), annualized alteration in bone density/strength by quantitative computed tomography and DXA, and secondarily, with incident clinical fractures and radiographic vertebral fractures. They analyzed data from the Age Gene/Environment Susceptibility-Reykjavik study. In women (n = 148) and men (n = 150), the mean ± SD age at baseline was 80.9 ± 4.2 and 82.6 ± 4.2 years, respectively. In women and in men, the mean baseline BMAT was 55.4% ± 8.1% and 54.1% ± 8.2%, respectively. Findings revealed greater loss of trabecular bone at the spine and femoral neck, and greater loss of spine compressive strength, in relation to greater BMAT in older women.