Bordewijk EM, et al. - Researchers investigated the cost-efficacy of six cycles of ovulation induction with gonadotrophins vs six cycles of ovulation induction with clomiphene citrate (CC) with or without IUI in normogonadotropic anovulatory women not pregnant after six ovulatory cycles with CC. In this economic evaluation of ovulation induction with gonadotrophins compared with CC with or without IUI performed in a two-by-two factorial multicentre randomized controlled trial in normogonadotropic anovulatory women not pregnant after six ovulatory cycles with CC, they included costs of medication, cycle monitoring, interventions, and pregnancy leading to live birth. Findings revealed both gonadotrophins and IUI as more expensive when compared with CC and intercourse. Compared to CC, gonadotrophins exhibited higher efficacy.