Sopfe J, Campbell K, Keating AK, et al. - In the present study, the researchers sought to identify risk factors for, and consequences of, higher glycemic variability in hematopoietic stem cell transplant (HSCT) patients. Records for a cohort of 344 patients, age 0‐30 years, who underwent first HSCT from 2007 to 2016 at Children's Hospital Colorado have been retrospectively reviewed. Glucose coefficients of variation (CV) were examined for HSCT days −14 to 0 and 0‐30, and patients were evaluated for potential risk factors and outcomes. Independent of HSCT type, doubling of pre‐HSCT glucose CV was related to a 4.91‐fold increased hazard of infection and increased risk for intensive care hospitalization for allogenic HSCT patients. Multivariable analysis showed that allogeneic HSCT patients had a 1.40‐ and 1.38‐fold increased hazard of death for every doubling of pre‐HSCT and day 0‐30 glucose CV, respectively. Just as with higher mean glucose, higher glycemic variability in the pediatric HSCT population is independently linked to significantly increased morbidity.