Billion L, Charleer S, Verbraeken L, et al. - In a Belgian real-world setting of adult people with type 1 diabetes (PWD1) who were using intermittently scanned or real-time continuous glucose monitoring (isCGM or rtCGM), switching to Fiasp was related to a 5% increase in time in range (TIR) after 12 months, corresponding to 75 minutes per day, in addition to less time spent below and above range.

• Data were analyzed from 438 adult PWD1 (60% men, age 44.6 ± 16.2 y, diabetes duration 21.5 ± 14.0 y, isCGM/rtCGM: 391/47, MDI/CSII: 409/29), who started Fiasp between January 2018 and May 2020.

• TIR increased from 50.3 ± 15.6% to 54.3 ± 15.1% at 6 months and 55.5 ± 15.2% at 12 months, equating to 57 minutes/day at 6 months and 75 minutes/day at 12 months.

• At 6 and 12 months, T <  54 mg/dL changed from 3.1 ± 3.3% to 3.1 ± 3.7% and 2.5 ± 3.0%, respectively.

• T > 180 mg/dL also declined from 42.3 ± 16.7% at the start by 4.2% at 6 months and by 4.6% at 12 months.

• The percentage of patients achieving TIR > 70% increased from 11.0% to 14.8% and those spending <4% at time < 70 mg/dL increased from 36.1% to 42.1%.

• HbA1c, insulin doses, and BMI did not significantly change after 12 months.