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Glomerular filtration rate: A prognostic marker in atrial fibrillation- a sub-analysis of the ATA-AF

Clinical Cardiology Aug 30, 2018

Proietti R, et al. - Researchers assessed estimated glomerular filtration rate (eGFR) as an independent prognostic marker of cardiovascular mortality and morbidity in atrial fibrillation (AF) patients examined in this sub-analysis of the AntiThrombotic Agents Atrial Fibrillation (ATA-AF), which included 7,148 patients with AF from 360 Italian centers. For 1,097 AF patients with eGFR data available and 1-year clinical follow-up, they calculated eGFR from data reported in patient notes or hospital database. At follow-up, cardiovascular mortality and/or hospital admission for cardiovascular causes was evaluated as the endpoint. Those with eGFR below 60 ml/min/1.73m2 were found to have a higher endpoint incidence by the Kaplan-Meyer curve. According to the findings of this post-hoc analysis, an impaired eGRF was independently associated with worse prognosis among patients with AF.
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