Gestational weight gain and rate of late-onset preeclampsia: A retrospective analysis on 57,000 singleton pregnancies in reunion island
BMJ Open Aug 03, 2020
Robillard PY, Dekker G, Boukerrou M, et al. - Researchers sought to determine if the incidence of late-onset preeclampsia (LOP) is affected by application of optimal gestational weight gains (optGWG) in a population of singleton term pregnancies (≥ 37 weeks gestation). They conducted an 18.5-year-observational cohort study (2001–2019) of 66,373 singleton term pregnancies with a live birth, and 716 LOP (≥37 weeks, LOP37). Among these, the GWG could be determined in 87% of cases. Analyses suggest that in case of attaining an optGWG, overweight and obesity may not result in a higher risk of developing LOP at term. They suggest a possible effectiveness of implementing targeted and strictly monitored interventions on achieving an optGWG for reducing the rate of LOP and this strategy would have the potential to halve its rate in women with overweight/obesity. Findings thereby indicate a potentially achievable pathway to actively counterbalance the morbid effects of high BMIs.
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