Soares RR, Gopal AD, Parikh D, et al. - In this retrospective, cross-sectional study, researchers identified geographic and socioeconomic variables predictive of residential proximity to neovascular age-related macular degeneration (nAMD) clinical trial locations. Census-tract level data from public datasets and trial-level data from ClinicalTrials.gov have been analyzed. They measured the driving distance (> 60 miles) and time (> 60 minutes) from the population-weighted United States (US) census tract centroid to the nearest clinical trial site. Lower odds of traveling > 60 miles to the nearest nAMD trial site were related to census tracts with a higher percentage of blacks, Hispanics and Asians, as compared to whites, and a lower percentage of the population < 200% of the federal poverty level. In time traveled > 60 minutes, similar predictors were discovered. In the United States, there are regional differences in clinical trial sites for nAMD.