Lu R, Zhao X, Li J, et al. - In this study, researchers did next-generation sequencing of samples from bronchoalveolar lavage fluid and cultured isolates from nine inpatients, eight of whom had attended the Huanan seafood market in Wuhan. Researchers obtained complete and partial 2019-nCoV genome sequences were from these individuals. The ten genome sequences of 2019-nCoV collected from the nine individuals were extremely similar, showing more than 99·98% sequence identity. 2019-nCoV is adequately divergent from SARS-CoV to be recognized a new human-infecting betacoronavirus. An animal sold at the seafood market in Wuhan might describe an intermediate host helping the emergence of the virus in humans, although our phylogenetic analysis suggests that bats might be the original host of this virus. In humans, structural analysis implies that 2019-nCoV might be able to bind to the angiotensin-converting enzyme 2 receptors. The further development, adaptation, and spread of this virus warrant urgent research.