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Gender differences among patients hospitalized with cirrhosis in the United States

Journal of Clinical Gastroenterology Apr 10, 2019

Rubin JB, et al. - Because gender disparities exist in outcomes among cirrhosis patients, researchers assessed the role of gender on hospital course and in-hospital outcomes in cirrhosis patients to help better understand these disparities. Data were analyzed from the National Inpatient Sample (NIS), years 2009 to 2013, to identify patients with any diagnosis of cirrhosis. The cohort included 553,017 cirrhosis patients admitted between 2009 and 2013. Women have lower rates of hepatic decompensating events and higher rates of nonhepatic comorbidities and infections in patients hospitalized with cirrhosis, resulting in lower in-hospital mortality. Women were more likely to have comorbidities with non-cirrhosis than men, including diabetes and hypertension, but were less likely to have most complications with cirrhosis, including ascites and variceal bleeding. Understanding differences in indications for and disposition after hospitalization can help develop gender-specific cirrhosis management programs to improve long-term outcomes in women and men with cirrhosis.
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